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In its current study, the gaps still have to be filled: how is the CYP 26B1 gradient controlled, how to attach to retino acid Shox The causes of the gene, and the key flow determine the structure of certain structures such as humor or radius bone structure.
From healing to regeneration
Monaghan explains that the aquotols do not have a “magic gene” for regeneration, but shares the same basic genes as humans. “There are the main differences Accessibility Between these genes. Injuries between humans activates genes that induce stains, where there are in salamanders Cell D-Differentition: Cells return to a fetus, where they can respond to signals like retino acids. This ability to return to a ‘developmental state’ is the basis of their regeneration, “the researcher explained.
So, if human beings have the same gene, why can’t we resume? “The difference is that Salmanander may re -emerge [developmental] Program after injury. “Humans – they simply cannot access the path to this development during the initial development before birth,” to understand how my dream and the dream of the community can convert from the stain to Blastma.
James Monaghan.Photograph: Allisa Stone/North -East University
Monaghan says that theoretically, human DNA will not be required to induce regeneration, but it is not necessary to interfere with the right time and space with the regulatory molecules. For example, molecular paths that signal a cell located on the elbow on the pink side – and not the thumb – can be re -activated in a regenerative environment using the technology like CRISPR. “This understanding can be applied to stem cell therapy. Currently, ‘they do not know where they are’ when they are replaced. If they can be programmed with precise positional signals, they can properly integrate the damaged tissue and contribute to structural regeneration, such as a complete hurry.
After years of work, the role of retino acids – Studed since 1981 – This is the source of deep satisfaction for Monahahan. The scientist imagined a future where a patch placed on a lesion could reactivate development programs in human cells, imitating the regenerative process of Salamander. Although not immediate, he believes that cell engineering is already a goal within the reach of science to persuade the regeneration.
He reflects how Acolotle has spent the second scientific life. “It was a dominant model a hundred years ago, then disabled for decades and now thanks to modern equipment like gene editing and cell analysis. The team can study any genes and cells during the regenerative process.
This story was originally attended Wired In Spanish And have been translated from Spanish.