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Nucleus genomics, a genetic testing startup founded by Kian Sadighi, 25 years old, Was initially launched in 2021 To calculate the patient’s risk for a specific disease.
However, it has been supporting the debate over the years for years that claim to tell people how their genetics relate to complex issues, including their IQ.
Wednesday, it spreads controversy at an ear dividing level when it announced a new product called the nucleus fetus With a tweet It was said: “Every parent wants to give their children more than them. For the first time in human history, the nucleus adds a new tool to that promise.”
The nucleus states that it is not only for well-known genes for well-known genes that have high possibilities like breast cancer, but also for presence-laing, height, hair color, eye-color IQ and anxiety and complicated health features like ADHD.
The launch video includes a screen shot of a comparison menu. The idea is to help the parent to pick up which fetuses to pick up and which is probably to cancel it.
The genetic test of the fetus cannot be heard. IVF physicians Can test for The genes that can cause conditions like down syndrome, or when parents know that they are at high risk for certain genetic disorders like cystic fibrosis.
But the nucleus is not doing so. A spokesman said it was using the controversial “polygenic score” to determine the “complicated genetic results such as intellect and anxiety”.
According to the National Human Genome Research Institute, polygenic scores only calculate the possibilities of a certain complex illness, mainly in the population. “A polygenic risk score can only explain the relative risk for a disease,” Says NHGRThe This is not like discovering a particular gene, such as BRCA 1 gene mutation, which is the absolute risk of breast cancer, “gives” a person 60-80% to a person Says NHGRThe
Physicians usually have a reason not to use these national tests for individuals. “Polygenic risk scores are not yet regularly used by health professionals because there is no guideline for practice and researchers are still improving how these scores are generated,” According to NHGRThe
The nucleus protects that its procedure can be used to determine the risk of a person. The spokesperson pointed to us A 2018 paper Where the authors say they have developed a valid method for five common diseases: coronary arteries, attrial fibrillation, type 2 diabetes, inflammatory intestines and breast cancer.
This paper was in favor of screening to help make the lifestyle or therapeutic decision of people similar to the initial concept of the nucleus.
Wednesday’s tweets were promising parents that the nucleus could help their designer baby create. It has now been viewed more than 4 million and has hundreds of comments, many of them disbelieve in disbelief that it acts as a promise, or the horror of the concept.
One VC chimmed In the discussion, “I was going to type something like Noah, but the reality of it made me so much nausea.”
Nucleus has felt this kind of debate before TechCrunch has previously reportedWhen it was declared a $ 14 million series earlier this year. Startup is supported by Founder Fund, Alexis Ohanian 776, And including Angels Adrian Aun (Forward Health CEO), Brent Sanders (Allergan’s former CEO) and Mattio Francesche (eight sleep CEO).
Last year, Sadighi launched the nucleus IQ, which is supposed to tell users how much their genetics affect the intelligence. The product was exploded As “bad science and big business” By some critics. Sarcasm Reveal a long defense About his organization’s method.
Nevertheless, adults say that they are genetically smart, it’s a thing. IVF told parents that they could choose the presence and other complex features for their kids, it is, Many will argueSomething else.
Nucleus Currently IVF Lab Partners are not conducting this national examination through In itself, Wall Street has reported the journal. It is partnership with the genomic forecast, which works with IVF clinics. A genomic executive told WSGE that many parents request detective exams and do not provide it. Parents can voluntarily upload genetic data information to the nucleus if they want to follow it.
Or, as Sadighi said in the launch video that parents were noticed: “So long ago IVF -1 does not give birth to fear and test tube children’s scandal,” he said. “The controversial that was once controversial is now a daily practice. In the case of genetic optimization it is the same true The technology is here and it is here to be here.”