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When doing serious treatment Burns and trauma, skin regeneration can be the subject of life or death. The top layer of the skin from anywhere else in the body is usually treated with a thin layer of epidermis. However, this method not only gives up big spots, it does not restore the skin to its original functional condition. If not dermis, the bottom layer under the epidermis is blood vessels and nerves, re -generated, it cannot be considered as normal living skin.
Now, Swedish researchers have brought the drug closer to the working skin to be reproduced by working. They have artificially developed 3D bioprinting techniques to create dense skin that is vascularized, which means it has a blood vessels. One technique produces the skin that is filled with cells and the other produces indiscriminate -shaped blood vessels in the tissue. The two technologies take different approaches for the same challenge. The procedure has been given outlined Two Study Advanced Health Care Materials Published in Journal.
“The dermis is so complicated that we can’t raise it in any labs. We don’t know what its ingredients are,” Linoking University Associate Professor Johan Junner and Plastic Surgery experts who were led by this job, who led the work, said he said. StatementThe “That’s why we and many others think that we can probably replace the building blocks and then make the body the dermis itself.”
Junkor and his team designed a bio-ink called “Kink” so that fibroblasts that produce dermal materials such as collagen, elastin and hyaluronic acid-Six spongy gelatin is cultured on the surface of the grain and a hyaluronic acid gel. By using 3D printer, this ink is made three -dimensional, they were able to create a skin structure filled with high density cells.
Researchers have confirmed in replacement tests using rats to replace the rats that researchers confirmed that the tissue -cut pie Got it, it indicates that the terms of the long -term tissue fixation were met.
The blood vessels play an important role in the construction of artificial tissue. Without the blood vessels, all the cells that cannot be equally carried in oxygen and nutritional cells are considered how many cells are cultured to create a tissue model. And without the blood vessels, the cells of the tissue die as the tissue structure increases.
The research team also created a technology called Refresh (Free-Vasman suspended hydrogel filament), which enables the flexible construction of artificial tissues in artificial tissues by printing and decorating hydrogel threads, a gel that 98 percent water. These threads can maintain their size even though they are much stronger and tied or breakded than ordinary gel materials. Furthermore, they also have shape-memory features that allow them to return to the original form despite being crushed.
